К содержимому
learnspaceYOUR NEXT CHAPTER
ПРОСТРАНСТВО ОБУЧЕНИЯ
ГлавнаяКаталог курсовМоё обучениеCoursera

Знания без границ

Учитесь у лучших университетов и компаний мира.

Открыть Coursera
Интеграция
Пространство университета
Моё пространствоСтраница курса
↵
ЯЛичный кабинетСтудент
© 2026 LearnSpaceКаждый день — возможность узнать больше.Помощь
Bioinformatics: Introduction and Methods 生物信息学: 导论与方法 · LearnSpace
Назад в каталог
courseraЗдоровье

Bioinformatics: Introduction and Methods 生物信息学: 导论与方法

Курс от Peking University
Уровень не указан≈ 25.6 чКитайский (Китай)
О курсеНавыкиПрограммаПреподаватели

О курсе

A big welcome to “Bioinformatics: Introduction and Methods” from Peking University! In this MOOC you will become familiar with the concepts and computational methods in the exciting interdisciplinary field of bioinformatics and their applications in biology, the knowledge and skills in bioinformatics you acquired will help you in your future study and research. Course materials are available under the CC BY-NC-SA License.

Навыки, которые вы освоите

BioinformaticsData ProcessingData MappingData Analysis SoftwareMolecular BiologyBiologyAnalysisLife SciencesMachine Learning AlgorithmsPredictive Analytics

Программа курса

14 модулей · 102 учебных материалов

01Introduction and History of Bioinformatics7 материалов

What is Bioinformatics

What is BioinformaticsВидео

History of Bioinformatics

History of BioinformaticsВидео

Overview of Bioinformatics in China and About This Course

Bioinformatics in Mainland ChinaВидеоAbout This CourseВидео

Review

Учитесь у экспертов

Ge Gao 高歌, Ph.D.

Assistant Professor, Principle Investigator

Liping Wei 魏丽萍, Ph.D.

Professor, Director

Bioinformatics: Introduction and Methods 生物信息学: 导论与方法
В каталоге вашей программы

Инвестируйте в себя

Новые знания — в удобное для вас время.

Начать на Coursera

Обучение откроется на Coursera
в новой вкладке

Обучение на Coursera

≈ 25.6 ч

14 модулей

Язык: Китайский (Китай)

Субтитры: Английский, Испанский, Русский, Французский

Часть программы вашего университета
Introduction and History of BioinformaticsЗадание

Supplementary

ReadingsЧтениеSlidesЧтение
02Sequence Alignment10 материалов

Sequence Alignment, Part I

Essential ConceptsВидеоGlobal Alignment by Dynamic ProgrammingВидео

Sequence Alignment, Part II

From Global to LocalВидеоAlignment with Affine Gap Penalty and Calculation of Time Complexity of The Needleman-Wunsch AlgorithmВидео

Interview with M. S. Waterman Waterman

Interview with M. S. Waterman WatermanВидео

Supplemental Lectures and Presentations

Supplement on Homology & Similarity, Similarity Matrix and Dot Matrix (English Subtitles)ВидеоStudent Presentation (English Subtitles)ВидеоReadingsЧтениеSlidesЧтение

Review

Sequence AlignmentЗадание
03Sequence Database Search6 материалов

Sequence Database Search

Sequence DatabasesВидеоBLAST Algorithm: A PrimerВидео

Student Presentation

Student Presentation (English Subtitles)Видео

Review

Sequence Database SearchЗадание

Supplementary

ReadingsЧтениеSlidesЧтение
04Markov Model7 материалов

Markov Model

From States to Markov ChainВидеоHidden Markov ModelВидеоPredict with Hidden Markov ModelВидео

Student Presentation

Student PresentationВидео

Review

Markov Model Задание

Supplementary

ReadingsЧтениеSlidesЧтение
05Next Generation Sequencing (NGS): Mapping of Reads From Resequencing and Calling of Genetic Variants11 материалов

Next Generation Sequencing (NGS)

From Sequencing to NGSВидеоReads Mapping and Variants CallingВидеоComputer Lab: Reads mapping and variant calling (English Subtitles)Видео

Supplemental Lectures

Supplement on reads mapping and variant calling (English Subtitles)ВидеоSupplement on genotyping (English Subtitles)ВидеоA quick tour to sequencer 1 - Ion Torrent PGM (English Subtitles)ВидеоA quick tour to sequencer 2 - 3730 Sanger sequencing (English Subtitles)Видео

Student Presentation

Student presentation (English Subtitles)Видео

Review

Next Generation Sequencing (NGS)Задание

Supplementary

ReadingsЧтениеSlidesЧтение
06Functional Prediction of Genetic Variants9 материалов

Variant Databases

Overview of the Problem ВидеоVariant Databases Видео

Predicting Methods

Conservation-Based and Rule-Based Methods: SIFT & PolyPhenВидеоClassifier-Based Methods: SAPREDВидео

Supplemental Lectures

Introduction to Support Vector Machine(SVM) (English Subtitles)Видео

Student Presentation

Student presentation (English Subtitles)Видео

Review

Functional Prediction of Genetic VariantsЗадание

Supplementary

ReadingsЧтениеSlidesЧтение
07Mid-term Exam1 материалов

Mid-term Exam

Mid-term ReviewЗадание
08Next Generation Sequencing: Transcriptome Analysis, and RNA-Seq8 материалов

Next Generation Sequencing: Transcriptome Analysis, and RNA-Seq

Transcriptome: An OverviewВидеоRNA-Seq: Mapping & AssemblingВидеоComputer Lab: RNA-seq Data Analysis RNA-seq (English Subtitles)Видео

Supplemental Lectures

Dr. Maynard Olson TalkВидео

Student Presentation

Student presentation (English Subtitles)Видео

Review

Next Generation Sequencing: Transcriptome Analysis, and RNA-SeqЗадание

Supplementary

ReadingsЧтениеSlidesЧтение
09Prediction and Analysis of Noncoding RNA9 материалов

Prediction and Analysis of Noncoding RNA

From Information to KnowledgeВидеоData Mining: Identify long ncRNAsВидеоData Mining: Differential Expression and ClusteringВидео

Supplemental Lectures

Feature selection and Clustering (English Subtitles)ВидеоA quick tour to sequencer - illumina HiSeq & MiSeq (English Subtitles)Видео

Student Presentation

Student Presentation (English Subtitles)Видео

Review

Prediction and Analysis of Noncoding RNAЗадание

Supplementary

ReadingsЧтениеSlidesЧтение
10Ontology and Identification of Molecular Pathways11 материалов

Ontology, Gene Ontology and KEGG Pathway Database

Ontology and Gene OntologyВидеоKEGG Pathway Database Видео

Annotations in Gene Ontology and Pathway Identification

Annotations in Gene Ontology ВидеоPathway Identification ВидеоAn Application: Common Molecular Pathways Underlying AddictionВидео

Supplemental Lectures

Brief Introduction to Database (English Subtitles)ВидеоKOBAS Demo (English Subtitles)Видео

Student Presentation

Student presentation on KOBAS (English Subtitles)Видео

Review

Ontology and Identification of Molecular PathwaysЗадание

Supplementary

ReadingsЧтениеSlidesЧтение
11Bioinformatics Database and Software Resources8 материалов

Overview and NCBI

Overview of ResourcesВидеоNational Center for Biotechnology InformationВидео

EBI, UCSC and Individual Resources

European Bioinformatics Institute ВидеоUCSC Genome BrowserВидеоIndividual ResourcesВидео

Student Presentation

CBI Resources Review (English Subtitles)Видео

Review

Bioinformatics Database and Software ResourcesЗадание

Supplementary

SlidesЧтение
12Origination of New Genes8 материалов

Origination of New Genes Part I

New Gene Evolution Detected by Genomic Computation: Basic Concepts and ExamplesВидеоNew Gene Evolution Detected by Genomic Computation: A Driver for Human Brain EvolutionВидео

Origination of New Genes Part II

A Human-Specific de novo Gene Associated with AddictionВидеоOrigination of de novo Genes from Noncoding RNAsВидео

Student Presentation

Student Presentation (English Subtitles)Видео

Review

Origination of New GenesЗадание

Supplementary

ReadingsЧтениеSlidesЧтение
13Evolution function analysis of DNA methyltransferase6 материалов

Evolution Function Analysis of DNA Methyltransferase

From Dry to Wet, an Evolutionary Story Part 1ВидеоProject background introduction by Dr. Gang PeiВидеоFrom Dry to Wet, an Evolutionary Story Part 2Видео

Supplemental Lectures

Talk with Dr. Gang Pei (English Subtitles)Видео

Student Presentation

Student Presentation (English Subtitles)Видео

Supplementary

SlidesЧтение
14Final Exam1 материалов

Final Exam

Final ExamЗадание