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Big Data, Genes, and Medicine · LearnSpace
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Big Data, Genes, and Medicine

Курс от The State University of New York
Продвинутый≈ 40.1 чАнглийский
О курсеНавыкиПрограммаПреподаватели

О курсе

This course distills for you expert knowledge and skills mastered by professionals in Health Big Data Science and Bioinformatics. You will learn exciting facts about the human body biology and chemistry, genetics, and medicine that will be intertwined with the science of Big Data and skills to harness the avalanche of data openly available at your fingertips and which we are just starting to make sense of. We’ll investigate the different steps required to master Big Data analytics on real datasets, including Next Generation Sequencing data, in a healthcare and biological context, from preparing data for analysis to completing the analysis, interpreting the results, visualizing them, and sharing the results. Needless to say, when you master these high-demand skills, you will be well positioned to apply for or move to positions in biomedical data analytics and bioinformatics. No matter what your skill levels are in biomedical or technical areas, you will gain highly valuable new or sharpened skills that will make you stand-out as a professional and want to dive even deeper in biomedical Big Data. It is my hope that this course will spark your interest in the vast possibilities offered by publicly available Big Data to better understand, prevent, and treat diseases.

Навыки, которые вы освоите

R ProgrammingBioinformaticsData CleansingPredictive ModelingMolecular BiologyBiostatisticsData PresentationStatistical ProgrammingAdvanced AnalyticsData MiningMedical Science and ResearchStatistical AnalysisBiomedical TechnologyStatistical MethodsInformaticsHealth InformaticsAnalyticsR (Software)Big DataPredictive Analytics

Программа курса

6 модулей · 145 учебных материалов

01Genes and Data20 материалов

Introduction to the Module

Introduction to the CourseВидеоIntroduction to ModuleВидео

Biological Terminology, DNA, and RNA

DNA and GenesВидеоRNA and ProteinsВидео

Учитесь у экспертов

Isabelle Bichindaritz

Associate Professor

Big Data, Genes, and Medicine
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Обучение откроется на Coursera
в новой вкладке

Обучение на Coursera

≈ 40.1 ч

6 модулей

Язык: Английский

Субтитры: Арабский, Французский, Бенгальский, Украинский, Китайский (Китай), Греческий, Итальянский, Бразильский португальский, Нидерландский, Корейский, Немецкий, Пушту, Урду, Русский, Тайский, Индонезийский, Шведский, Турецкий, Азербайджанский, Испанский, Дари, Хинди, Японский, Казахский, Венгерский, Польский

Часть программы вашего университета
DNA, RNA, Genes, and ProteinsЗадание

From Genes to Proteins

Transcription ProcessВидеоTranscription AnimationВидеоTranslation ProcessВидеоTranslation AnimationВидеоTranscription and Translation ProcessesЗадание

Data, Variables, and Datasets

Data, Variables, and Big DatasetsВидеоData, Variables, and Big DatasetsЗадание

First Steps in Working with Datasets

Working with cBioPortal - Genetic Data AnalysisВидеоWorking with cBioPortal - Gene NetworksВидеоWorking with cBioPortalЗадание

Assessment

Module 1 DiscussionОбсуждениеModule 1 QuizЗаданиеModule 1 cBioPortal Data AnalyticsЧтениеModule 1 cBioPortal Data AnalyticsЗадание

Resources

Module 1 ResourcesЧтение
02Preparing Datasets for Analysis28 материалов

Introduction to the Module

Introduction to ModuleВидео

Locating and Downloading Datasets

Datasets and FilesВидеоData SourcesВидеоDatasets and FilesЗадание

Data Preprocessing

Importance of Data PreprocessingВидеоData Preprocessing TasksВидеоData Preprocessing TasksЗадание

Missing Values

Replacing Missing ValuesВидеоReplacing Missing ValuesЗадание

Normalizing and Discretizing Data

Data NormalizationВидеоData DiscretizationВидеоNormalization and DiscretizationЗадание

Data Reduction

Feature SelectionВидеоData SamplingВидеоData ReductionЗадание

Introduction to R Language

Principles of RВидеоR LanguageВидеоWorking with RЗадание

R notebook

Module 2 NotebookЛабораторнаяJupyter Notebooks 101ВидеоJupyter Notebooks EssentialsЧтениеNotebook Module 2 TutorialЧтение

Assessment

Module 2 DiscussionОбсуждениеModule 2 QuizЗаданиеModule 2 R Data PreprocessingЧтениеModule 2 NotebookЛабораторнаяModule 2 R Data PreprocessingЗадание

Resources

Module 2 ResourcesЧтение
03Finding Differentially Expressed Genes22 материалов

Introduction to the Module

Introduction to ModuleВидео

Feature Selection Methods

Overview of Feature Selection MethodsВидеоFilter MethodsВидеоWrapper MethodsВидеоFeature Selection MethodsЗадание

Evaluation of Feature Selection Methods

Evaluation SchemesВидеоEvaluation SchemesЗадание

Feature Selection for Gene Expression Data

Selecting Differentially Expressed GenesВидеоDifferentially Expressed GenesЗадание

Heatmaps and Visualizations

HeatmapsВидеоHeatmapsЗадание

Feature Selection with R

R Scripts for Feature SelectionВидео

R notebook

Module 3 NotebookЛабораторнаяNotebook Module 3 TutorialЧтениеJupyter Notebooks EssentialsЧтениеJupyter Notebooks 101Видео

Assessment

Module 3 DiscussionОбсуждениеModule 3 QuizЗаданиеModule 3 R Finding Differentially Expressed GenesЧтениеModule 3 NotebookЛабораторнаяModule 3 R Finding Differentially Expressed GenesЗадание

Resources

Module 3 ResourcesЧтение
04Predicting Diseases from Genes28 материалов

Introduction to the Module

Introduction to ModuleВидео

Classification and Prediction Methods

Overview of Classification and Prediction MethodsВидеоOverviewЗаданиеClassification Methods Based on AnalogyВидеоClassification with AnalogyЗаданиеClassification Methods Based on RulesВидеоClassification based on RulesЗаданиеClassification Methods Based on Neural NetworksВидеоClassification with Neural NetworksЗаданиеClassification Methods Based on StatisticsВидеоClassification based on StatisticsЗаданиеClassification Methods Based on ProbabilitiesВидеоClassification based on ProbabilitiesЗаданиеPrediction MethodsВидеоPrediction ModelsЗадание

Evaluation of Prediction Performance

Evaluation SchemesВидеоEvaluation SchemesЗадание

Combining Feature Selection and Prediction

Prediction WorkflowВидео

Classification and Prediction with R

R Scripts for PredictionВидео

R notebook

Module 4 NotebookЛабораторнаяJupyter Notebooks EssentialsЧтениеJupyter Notebooks 101ВидеоNotebook Module 4 TutorialЧтение

Assessment

Module 4 DiscussionОбсуждениеModule 4 QuizЗаданиеModule 4 R Predicting Diseases from GenesЧтениеModule 4 R Predicting Diseases from GenesЗадание

Resources

Module 4 ResourcesЧтение
05Determining Gene Alterations23 материалов

Introduction to the Module

Introduction to ModuleВидео

Gene Alterations and their Consequences

Overview of Gene AlterationsВидеоGene AlterationsЗадание

Genetic Mutations

Genetic MutationsВидеоFinding Genetic MutationsВидеоGene MutationsЗадание

Methylation

MethylationВидеоMethylationЗадание

Copy Number Alterations

Copy Number AlterationsВидеоCopy Number AlterationsЗадание

Genomic Alterations and Gene Expressions

Genomic Alterations and Gene ExpressionsВидеоGenomic Alterations and Gene ExpressionsЗадание

Gene Alterations with R

R Scripts for Gene AlterationsВидео

R notebook

Module 5 NotebookЛабораторнаяJupyter Notebooks 101ВидеоNotebook Module 5 TutorialЧтениеJupyter Notebooks EssentialsЧтение

Assessment

Module 5 DiscussionОбсуждениеModule 5 Quiz (Temporary)ЗаданиеModule 5 QuizЗаданиеModule 5 R Gene AlterationsЧтениеModule 5 R Gene AlterationsЗадание

Resources

Module 5 ResourcesЧтение
06Clustering and Pathway Analysis24 материалов

Introduction to the Module

Introduction to ModuleВидео

Clustering Overview

Overview of Clustering MethodsВидеоSimilarity AssessmentВидеоClusteringЗадание

Clustering Methods

Clustering with KMeansВидеоDensity Based ClusteringВидеоHierarchical ClusteringВидеоClustering MethodsЗадание

Pathway Analysis

Pathway AnalysisВидеоPathway DiscoveryВидеоPathway VisualizationВидеоPathwaysЗадание

Clustering and Pathways with R

R Scripts for Clustering and Pathway AnalysisВидео

R notebook

Module 6 NotebookЛабораторнаяJupyter Notebooks 101ВидеоJupyter Notebooks EssentialsЧтениеNotebook Module 6 TutorialЧтение

Assessment

Module 6 DiscussionОбсуждениеModule 6 QuizЗаданиеModule 6 R Clustering and PathwaysЧтениеModule 6 R Clustering and PathwaysЗадание

Resources

Module 6 ResourcesЧтение

Concluding Remarks

Concluding RemarksВидеоAcknowledgementsЧтение