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Personalised Medicine from a Nordic Perspective · LearnSpace
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Personalised Medicine from a Nordic Perspective

Курс от University of Copenhagen, University of Iceland
Средний≈ 14.3 чАнглийский
О курсеНавыкиПрограммаПреподаватели

О курсе

The technical revolution has generated large amounts of data in healthcare and research, and a rapidly increasing knowledge about factors of importance for the individual’s health. This holds great potential to support a change from the one-size-fits-all paradigm to personalised or precision medicine, to guide and thereby improve each health decision of expected benefit for the patient. The SARS-CoV-2 pandemic has contributed to a great public and political awareness of the importance of personalised medicine, where the influence of host factors like age, sex, obesity, smoking, co-morbidities etc. confer increased risk of serious COVID-19 illness. It is expected that in the near future, a more systematic and data-driven approach for prediction and risk stratification of COVID-19 patients and many other patient groups, will increase and improve due to better understanding of disease pathology, including the influence of genetic variability and biomarkers on disease risk and outcome. The Nordic countries have unique welfare systems with general access to healthcare, and longitudinal nationwide health databases and biobanks. This infrastructure combined with unique person identifiers creates an optimal setting for personalised medicine development, and the Nordic model of research, translation, care and education can serve as a forefront example for the rest of the world. The course in Personalised medicine from a Nordic perspective will introduce, describe, define and discuss the concept of personalised medicine from the aspect of the patient, health-care and the infrastructure available to generate a learning environment that is integrated with everyday care of patients. The course also covers communication of risk and the ethical, legal and social aspects of personalised medicine and presents examples where personalised medicine approach is already used in routine care. The course was initiated by Faculty leaders in the Education Working Group of Nordic Medical Schools and received funding from the Joint Committee of the Nordic Medical Research Councils (NOS-M). Experts from all the Nordic countries participate in the course: Saedis Saevarsdottir, Sisse Ostrowski, Hans Tomas Björnsson, Richard Rosenquist Brandell, Henning Bundgaard, Engilbert Sigurðsson, Aarno Palotie, Ole A Andreassen, Runolfur Palsson, Alma Möller, Søren Brunak, Johan Askling, Carsten Utoft Niemann, Rudi Agius, Sofia Ernestam, Saemundur Oddsson, Henrik Ullum, Kari Stefansson, Patrick Sulem, Simon Rasmussen, Jens Lundgren, Anders Perner, Merete Lund Hetland, Heidi Bentzen, Henning Langberg, Sigurdur Kristinsson, Thor Aspelund, Jeanette Knox, David Arnar, Sigurdis Haraldsdottir, Hakon Heimer, Lone Frank, Mette Nordahl Svendsen, Bjorn Hofmann, and Morten Søgaard.

Навыки, которые вы освоите

Precision MedicinePatient-centered CareBioinformaticsData-Driven Decision-MakingHealthcare EthicsInnovationPatient CommunicationGeneral Data Protection Regulation (GDPR)Healthcare Industry KnowledgeClinical ResearchHealth TechnologyClinical Research EthicsHealth InformaticsRisk AnalysisData EthicsMedical Science and ResearchHealth PolicyHealth CareData ScienceHealth Systems

Программа курса

6 модулей · 82 учебных материалов

01Introduction to personalised medicine14 материалов

Welcome to the course

Introduction to Personalised Medicine from a Nordic Perspective – Saedis Saevarsdottir, Sisse OstrowskiВидео

Applied examples

Applied examples – Hans Tomas Björnsson, Richard Rosenquist Brandell, Henning BundgaardВидеоFurther readingЧтение

What is personalised medicine?

What is personalised medicine? – Sisse Ostrowski

Учитесь у экспертов

Sisse Rye Ostrowski

Professor

Saedis Saevarsdottir

Professor

Personalised Medicine from a Nordic Perspective
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≈ 14.3 ч

6 модулей

Язык: Английский

Субтитры: Арабский, Французский, Украинский, Китайский (Китай), Греческий, Итальянский, Бразильский португальский, Нидерландский, Корейский, Немецкий, Русский, Тайский, Индонезийский, Шведский, Турецкий, Испанский, Хинди, Японский, Казахский, Польский

Часть программы вашего университета
Видео
What is personalised medicine?Задание
Precision medicine: discovering clinically relevant and mechanistically anchored disease subgroups at scaleЧтение
Classification, ontology, and precision medicineЧтение
Further readingЧтение

Why the Nordic perspective?

Why the Nordic perspective? – Saedis SaevarsdottirВидеоWhy the Nordic perspective?ЗаданиеFurther readingЧтениеChallenges and opportunities in your countryОбсуждение

Initiatives to address unmet needs in common diseases

(Suited for listening) Initiatives to address common diseases – Engilbert Sigurðsson, Aarno Palotie, Ole A Andreassen, Runolfur PalssonВидеоFurther readingЧтение
02Health information used in personalised medicine17 материалов

What is health data? Data generation pre-birth and throughout life

What is health data? Data generation pre-birth and throughout life – Alma MöllerВидео

Patient information used to generate personalised medicine

Patient information used to generate personalised medicine – Johan AsklingВидеоPatient information used to generate personalised medicineЗаданиеPatient-reported outcomes in the Swedish National Quality RegistersЧтениеPatient-reported outcome and experience measuresЧтение

Optimizing clinical decision making with data-driven approaches

Optimizing clinical decision making with data-driven approaches – Carsten Utoft NiemannВидеоOptimizing clinical decision making with data-driven approachesЗаданиеReal-world data-driven machine learning in CLLЧтение

Data cleaning and validation

Data cleaning and validation – Rudi AgiusВидеоData cleaning and validationЗаданиеFurther readingЧтение

Mapping disease trajectories from longitudinal health data

Mapping disease trajectories from longitudinal health data – Søren BrunakВидеоTime-ordered comorbidity correlationsЧтениеFurther readingЧтение

Digital tools for patient engagement

Digital tools for patient engagement – Sofia Ernestam, Saemundur OddssonВидеоOptional: Explore the digital tools ЧтениеCommunicating polygenic and non-genetic risk...Чтение
03Biomarkers, genetics, and omics11 материалов

What is a biomarker?

What is a biomarker? – Saedis SaevarsdottirВидеоWhat is a biomarker?ЗаданиеFurther readingЧтение

Studying and implementing useful biomarkers in clinical practice

Studying and implementing useful biomarkers in clinical practice – Henrik Ullum, Henning BundgaardВидео

Clinical sequencing and genetic testing – ‘science fiction’ a few years ago

(Suited for listening) Clinical sequencing and genetic testing – 'science fiction' a few years ago – Hans Tomas Björnsson, Patrick SulemВидеоVideo: The future of genomics: 10 bold predictionsPLUGIN

Omics and beyond – smart ways to identify biomarkers

Omics and beyond – smart ways to identify biomarkers – Simon RasmussenВидеоOmics and beyond - smart ways to identify biomarkers ЗаданиеMulti-omics approaches to diseaseЧтение

The use of genetic information in clinical medicine

The use of genetic information in clinical medicine – David O. ArnarВидеоUnexplained sudden death: next-generation sequencing to the rescue?Чтение
04Evidence and documentation for clinical efficacy of personalised medicine11 материалов

What is evidence? Shift in the paradigm driven by personalised medicine

What is evidence? Shift in paradigm driven by personalised medicine – Jens LundgrenВидеоWhat is evidence? Shift in paradigm driven by personalised medicineЗаданиеEvidence-based medicine: What it is and what it isn'tЧтениеFurther readingЧтение

Novel trials to generate evidence

Novel trials to generate evidence – Merete Lund Hetland, Anders PernerВидеоNovel trials to generate evidenceЗаданиеFurther readingЧтение

How to generate evidence from a legal and ethical perspective

How to generate evidence from a legal and ethical perspective – Heidi BentzenВидеоHow to generate evidence from a legal and ethical perspectiveЗаданиеFurther readingЧтение

Innovation: From research to clinical practice

Innovation: From research to clinical practice – Henning LangbergВидео
05Communication in personalised medicine16 материалов

Screening for rare and common diseases

Screening for rare and common diseases – Sigurdur KristinssonВидеоScreening for rare and common diseasesЗадание

How to communicate risk

How to communicate risk – Thor AspelundВидеоHelping patients decide: Ten steps to better risk communicationЧтениеFive ways to communicate risks so that patients understandЧтениеFurther readingЧтение

Patient-centred care as a complement to personalised medicine

Patient-centered care as a complement to personalised medicine – Jeanette KnoxВидеоPatient-centred care as a complement to personalised medicine ЗаданиеThe difference that kind and compassionate care makesЧтениеThe art of radical listeningЧтениеPatient-centered care and personalised medicineОбсуждениеFurther readingЧтение

Diagnosed with a risk variant?

Diagnosed with a risk variant? – Sigurdis HaraldsdottirВидеоFurther readingЧтение

Media hype and horror

Media hype and horror – Hakon Heimer, Lone Frank, Heidi BentzenВидеоPersonalised Medicine – Media hype and horrorОбсуждение
06Ethical, legal and social aspects of personalised medicine13 материалов

Ethical concerns

Ethical concerns – Mette Nordahl SvendsenВидеоEthical concernsЗадание

Legal regulation

Legal regulation – Heidi BentzenВидеоFurther readingЧтение

Ethical and social aspects

Ethical and social aspects – Bjørn HofmannВидеоEthical and social aspectsЗаданиеFurther readingЧтение

Why does industry invest in genetics and omics

(Suited for listening) Morten Søgaard, Pfizer – Why invest in genetics and omicsВидео(Suited for listening) Kari Stefansson, deCODE genetics – Why invest in genetics and omicsВидео

Reflections on the future

Reflections on the future – Saedis Saevarsdottir, Sisse OstrowskiВидеоFurther readingЧтениеCourse reflection and looking aheadОбсуждение

Other great learning resources and add you own

Other great learning resources – and add your ownОбсуждение