Pharmacotherapy: Understanding Biotechnology Products

О курсе

Welcome to "Pharmacotherapy: Understanding Biotechnology Products," a specialized course led by Dr. Charles Lee. This curriculum offers a comprehensive exploration of therapeutic protein products, spanning from laboratory bench research to clinical implementation. Students will begin by tracing the evolution of biotechnology, from ancient fermentation practices to modern breakthroughs like recombinant DNA (r-DNA) and hybridoma technology. The course delves into core technical principles, including vector technology, antisense oligonucleotides, and bioinformatics. Through case-based exercises, learners will analyze critical clinical challenges such as immunogenicity, the formation of Anti-Drug Antibodies (ADAs), and advanced formulation strategies like pegylation and targeted delivery. A significant focus is placed on establishing PK/PD correlations, where you will investigate the biochemical differences between biologics and small molecules to optimize individualized dosing regimens. Finally, the course surveys major therapeutic classes and the emerging market of biosimilars. By mastering these scientific principles, pharmacists will be empowered to serve as expert consultants to physicians and dedicated advocates for patient safety in the rapidly expanding biologics era.

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Hsiang-Yin Shawn Chen

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