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What Do Viruses Do And How Do We Control Them · LearnSpace
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What Do Viruses Do And How Do We Control Them

Курс от Imperial College London
Средний≈ 11.9 чАнглийский
О курсеНавыкиПрограммаПреподаватели

О курсе

This course describes how viruses interact with their hosts to infect, replicate, spread and cause disease. It looks at what controls the specificity of viruses for different host species and for different tissues within a host, also how this can lead to outbreaks and pandemics. It seeks to show how virus evolution is driven by the pressures to replicate and spread. Finally, it looks at how we can find antivirals and use them to control infections, distinguishing therapeutic approaches to prophylaxis by vaccination. On successful completion of the course, learners will be able to: 1. Identify key interfaces of virus: host interaction 2. Verify how transmission drives virus pathogenesis and shapes virus evolution 3. Demonstrate an understanding of how virus control with anti-virals differs from protection with vaccines. This is an intermediate series of courses intended for both clinical and non-clinical scientists who want to update their skills for work in clinical, academic, and pharmaceutical/bioscience industries, and is developed and delivered by experts working on viruses and novel vaccines. To be successful in this series of courses, you should have basic knowledge in biology, genetics, microbiology or related fields.

Навыки, которые вы освоите

Infectious DiseasesMicrobiologyPublic HealthEpidemiologyPathologyImmunologyChronic DiseasesBiologyLife SciencesDrug DevelopmentPharmacologyPublic Health and Disease PreventionMolecular Biology

Программа курса

5 модулей · 65 учебных материалов

01Pathogenesis – why and how do viruses cause disease14 материалов

Course introduction

Introduction to ‘What do viruses do and how do we control them?'Видео

Virus pathogenesis and virulence

Course syllabusЧтениеIntroduction to pathogenesis and virulenceЧтениеWhat do viruses do and how do we control them glossaryЧтение

Учитесь у экспертов

Mike Skinner

Emeritus Professor in Virology

What Do Viruses Do And How Do We Control Them
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Обучение откроется на Coursera
в новой вкладке

Обучение на Coursera

≈ 11.9 ч

5 модулей

Язык: Английский

Часть программы вашего университета
What do we mean by ‘pathogenesis’ and ‘virulence’?Видео

Viruses, disease and transmission

Introduction to viruses, disease and transmissionЧтениеWhy do viruses cause disease?ВидеоHow can viruses cause severe disease?ОбсуждениеHow does route of transmission affect pathogenesis?ВидеоViruses, disease and transmissionЗадание

Viruses causing disease

How do viruses cause disease?ВидеоWhy do diseases differ in severity between viruses and between hosts?ВидеоWhy don’t viruses kill us all?ВидеоSummative QuizЗадание
02Virus ‘lifestyles’ – why do some viruses cause short duration diseases and others cause cancer?12 материалов

Virus ‘lifestyles’

Introduction to virus lifestylesЧтениеVirus lifestylesВидеоTechniques for measuring virus load?Обсуждение

Acute, chronic, and latent infections

Introduction to acute, chronic and latent infectionsЧтениеAcute virus infectionsВидеоChronic virus infectionsВидеоLatent virus infectionsВидеоViruses lifestyles and viral infectionЗадание

Viruses in cancer and progressive diseases

Introduction to viruses in cancer and chronic diseasesЧтениеVirus families, their behaviour and links to human cancerЗаданиеViruses in cancer and progressive diseasesВидеоSummative quizЗадание
03Tissue tropism and host range – why do viruses infect different animals and cause different diseases12 материалов

Virus tissue and host range

Introduction to virus tissue and host rangeЧтениеWhat determines tissue and host range?ВидеоWhat makes a virus a specialist or a generalist?Видео

Factors influencing tissue and host range

Introduction to factors influencing tissue and host rangeЧтениеHow do receptors influence tissue and host range?ВидеоInterview - Positive and negative host restriction factorsВидеоWhat intracellular factors affect tissue and host range?ВидеоInterview - The role of latent virus RNAs as immunomodulators and their implication in cancer, and the role of EBV in MSВидеоVirus tissue and host rangeЗадание

Tissue and host range evolution

Introduction to tissue and host range evolutionЧтениеHow can the virus evolve to change its tissue and host range?ВидеоSummative QuizЗадание
04How and why do outbreaks and pandemics occur, and why do they often emerge from animals?12 материалов

Emergences of viruses from animals

Introduction to how and why outbreaks and pandemics occurЧтениеEmerging viruses from zoonotic origins and COVID-19ОбсуждениеDo all zoonotic virus infections lead to epidemics and pandemics?ВидеоWhy are we seeing so many emergences of viruses from animals?Видео

Animal viruses in humans

Introduction to animal viruses in humansЧтениеWhat determines whether an animal virus will become established in humans?ВидеоWhy are infections often more severe in their new host?ВидеоVirus lifestylesЗадание

Emerging virus evolution and severity

Introduction to emerging virus evolution and severityЧтениеKnown viruses from zoonotic originsОбсуждениеDo emerging viruses always evolve to be less severe in the new host?Видео

Summative quiz

Summative QuizЗадание
05How can we prevent and/or control virus infections and outbreaks?15 материалов

Antibiotics and antivirals

Introduction to how we prevent and control virus infections and outbreaksЧтениеWhy are viruses harder to target with therapeutics than bacteria?Видео

Outbreak prevention and control

Introduction to outbreak prevention and controlЧтениеWhat measures are available to prevent or control virus outbreaks?ВидеоInterview - The role of mass virus diagnostics in outbreak preventionВидео

Which antivirals and their timing

Introduction to which antivirals and their timingЧтениеHow do we decide what antivirals to use, and when?Видео

Virus resistance to antivirals

Introduction to virus resistance to antiviralsЧтениеHow do we handle virus resistance to antivirals?ВидеоWhat viruses do and how we control themЗадание

Pandemic prevention though outbreak responses

Introduction to pandemic prevention through outbreak responsesЧтениеAre there new ways we might prevent outbreaks?ВидеоInterview - Going forward with virology research to best prevent and control future outbreaksВидеоSummative QuizЗаданиеCourse SummaryВидео